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Version: 17.06d (Release date: 2017-06-26)
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Budesonide/Formoterol Fumarate Dihydrate Inhalation Aerosol (Code C71534)

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Terms & Properties

Preferred Name: Budesonide/Formoterol Fumarate Dihydrate Inhalation Aerosol

Definition: An inhalation aerosol formulation containing budesonide and the fumarate dihydrate salt of formoterol with anti-inflammatory and bronchial smooth muscle-relaxing activities. The synthetic corticosteroid steroid budesonide binds to intracellular glucocorticosteroid receptors (GRs), exhibiting inhibitory activities against multiple cell types and mediators associated with allergic inflammation. The long-acting beta-adrenergic receptor agonist formoterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP); increased intracellular cAMP result in the relaxation of bronchial smooth muscle and inhibition of the cellular release of mediators of immediate hypersensitivity, especially from mast cells.

Label: Budesonide/Formoterol Fumarate Dihydrate Inhalation Aerosol

NCI Thesaurus Code: C71534 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1121854  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Budesonide/Formoterol Fumarate Dihydrate Inhalation Aerosol
Symbicort Turbuhaler

External Source Codes: 
PDQ Closed Trial Search ID 579574
PDQ Open Trial Search ID 579574 (check for NCI PDQ open clinical trial info)
UMLS CUI C1121854

Other Properties:
     Name Value (qualifiers indented underneath)
code C71534
Legacy_Concept_Name Budesonide_Formoterol_Fumarate_Dihydrate
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C71534

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