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Version: 16.10e (Release date: 2016-10-31)
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Formoterol Fumarate/Roxithromycin (Code C71161)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Formoterol Fumarate/Roxithromycin

Definition: A combination preparation of the fumarate salt of a beta2-adrenergic receptor agonist and a macrolide antibiotic, with muscle-sparing and anti-cachexia effects. Formoterol appears to antagonize cachexia by reducing proteolysis mediated through the ubiquitin-protease pathway. Roxithromycin strongly inhibits inflammatory cytokine production and secretion from T cells and macrophages in vitro and in vivo. The combination exhibits a greater muscle sparing effect than either drug given individually at comparable doses.

Label: Formoterol Fumarate/Roxithromycin

NCI Thesaurus Code: C71161 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL376213  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
BetaMarc
Formoterol Fumarate/Roxithromycin

External Source Codes: 
PDQ Closed Trial Search ID 573071
PDQ Open Trial Search ID 573071 (check for NCI PDQ open clinical trial info)
NCI META CUI CL376213

Other Properties:
Name Value (qualifiers indented underneath)
code C71161
Legacy_Concept_Name Formoterol_Fumarate_Roxithromycin
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C71161

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