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Version: 17.06d (Release date: 2017-06-26)
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Anti-PSCA Monoclonal Antibody AGS-1C4D4 (Code C71157)

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Terms & Properties

Preferred Name: Anti-PSCA Monoclonal Antibody AGS-1C4D4

Definition: An IgG1k fully human monoclonal antibody directed against the human prostate stem cell antigen (PSCA) with potential antineoplastic activity. Anti-PSCA fully human monoclonal antibody MK4721 selectively targets and binds to PSCA, triggering complement-dependent cell lysis and antibody-dependent cell-mediated cytotoxicity in tumor cells expressing PSCA. PSCA is a glycosyl-phosphatidylinositol (GPI)-linked cell surface antigen found in cancers of the bladder, pancreas, and prostate.

Display Name: Anti-PSCA Monoclonal Antibody AGS-1C4D4

Label: Anti-PSCA Monoclonal Antibody AGS-1C4D4

NCI Thesaurus Code: C71157 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2347292  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
AGS-1C4D4
Anti-PSCA Monoclonal Antibody AGS-1C4D4
MK4721

External Source Codes: 
PDQ Closed Trial Search ID 570981
PDQ Open Trial Search ID 570981 (check for NCI PDQ open clinical trial info)
UMLS CUI C2347292

Other Properties:
     Name Value (qualifiers indented underneath)
code C71157
Contributing_Source CTRP
Legacy_Concept_Name Monoclonal_Antibody_MK4721
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Immunologic Factor

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C71157

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