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Version: 17.06d (Release date: 2017-06-26)
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Autologous Follicular Lymphoma-Derived Idiotype Vaccine (Code C71036)

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Terms & Properties

Preferred Name: Autologous Follicular Lymphoma-Derived Idiotype Vaccine

Definition: A patient-specific cancer vaccine directed against the soluble protein idiotype of an individual follicular lymphoma with potential antineoplastic activity. A patient-specific follicular lymphoma-derived anti-idiotype vaccine may be composed of a patient-specific, synthetic idiotype-related peptide (such as one corresponding to a hypervariable region of an IgG heavy chain) conjugated to the immunostimulant carrier protein keyhole limpet hemocyanin (KLH). Upon administration, this vaccine may induce an idiotype-specific cytotoxic T-lymphocyte (CTL) response against follicular lymphoma cells expressing the idiotype, resulting in tumor cell lysis.

Display Name: Autologous Follicular Lymphoma-Derived Idiotype Vaccine

Label: Autologous Follicular Lymphoma-Derived Idiotype Vaccine

NCI Thesaurus Code: C71036 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2346884  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Autologous Follicular Lymphoma-Derived Idiotype Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 572211
PDQ Open Trial Search ID 572211 (check for NCI PDQ open clinical trial info)
UMLS CUI C2346884

Other Properties:
     Name Value (qualifiers indented underneath)
code C71036
Contributing_Source CTRP
Legacy_Concept_Name Autologous_Follicular_Lymphoma-Derived_Idiotype_Vaccine
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C71036

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