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Version: 17.06d (Release date: 2017-06-26)
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Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine (Code C70674)

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Terms & Properties

Preferred Name: Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine

Definition: A peptide vaccine preparation, containing recombinant human epidermal growth factor (rEGF) linked to the Neisseria meningitidis-derived recombinant immunogenic carrier protein P64k (rP64k) and mixed with the immunoadjuvant Montanide ISA 51, with potential active immunotherapy activity. Recombinant human EGF-rP64K/Montanide ISA 51 vaccine may trigger a humoral immune response against vaccine rEGF and rP64K and, so, against endogenous EGF. Antibody-mediated inhibition of endogenous EGF binding to its receptor, epithelial growth factor receptor (EGFR), may result in the inhibition of tumor cell proliferation.

Label: Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine

NCI Thesaurus Code: C70674 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL376048  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Center of Molecular Immunology (CIMA) Epidermal Growth Factor (EGF) Vaccine
Center of Molecular Immunology Epidermal Growth Factor Vaccine
Cimavax
CimaVax
CIMAvax-EGF
CIMAvax EGF
CIMAvax Epidermal Growth Factor Vaccine
Recombinant Human EGF-P64K/Montanide Vaccine
Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 570107
PDQ Open Trial Search ID 570107 (check for NCI PDQ open clinical trial info)
NCI META CUI CL376048

Other Properties:
     Name Value (qualifiers indented underneath)
code C70674
Contributing_Source CTRP
Legacy_Concept_Name Recombinant_Human_EGF-rP64K_Montanide_ISA_51_Vaccine
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C70674

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