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Version: 17.06d (Release date: 2017-06-26)
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Norgestrel (Code C703)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Norgestrel

Definition: A synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes. This agent also exhibits antiproliferative activity in endometrial tissue and may exhibit chemopreventive and antineoplastic activities in endometrial carcinoma. (NCI04)

Display Name: Norgestrel

Label: Norgestrel

NCI Thesaurus Code: C703 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0028368  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(+/-)-13-Ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one
(17alpha)-(+/-)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one
Neogest
Norgestrel
NORGESTREL
Ovrette
Wy-3707

External Source Codes: 
CAS Registry Number 6533-00-2 (see NLM ChemIDplus info)
FDA UNII Code 3J8Q1747Z2
ChEBI ID CHEBI:7630 (see ChEBI info)
ChEBI ID CHEBI:50901 (see ChEBI info)
PDQ Closed Trial Search ID 39310
PDQ Open Trial Search ID 39310 (check for NCI PDQ open clinical trial info)
UMLS CUI C0028368

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Oral contraception
Chemical_Formula C21H28O2
code C703
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Norgestrel
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C703

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