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Version: 17.12d (Release date: 2017-12-26)
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Iodine I-123 Iodometomidate (Code C69137)

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Terms & Properties

Preferred Name: Iodine I-123 Iodometomidate

Definition: An iodine I-123 conjugate of metomidate (MTO) with potential application in adrenal imaging. Metomidate is a potent and selective inhibitor of the cytochrome P-450 enzymes, especially CYP11B1 (11 beta-hydroxylase) and CYP11B2 (aldosterone synthase). Because both CYP11B1 and CYP11B2 are expressed exclusively in the adrenal cortex, I-123 iodometomidate can be used as a radiotracer for adrenal scintigraphy.

Label: Iodine I-123 Iodometomidate

NCI Thesaurus Code: C69137 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL371853  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Iodine I-123 Iodometomidate

External Source Codes: 
PDQ Closed Trial Search ID 543155
PDQ Open Trial Search ID 543155 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C69137
Legacy_Concept_Name Iodine_I_123_Iodometomidate
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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