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Version: 17.06d (Release date: 2017-06-26)
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Adenovirus Encoding Human Aquaporin-1 (Code C68932)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Adenovirus Encoding Human Aquaporin-1

Definition: A replication-deficient, recombinant adenovirus encoding human aquaporin-1 with potential membrane water channel activity. Upon transfection of salivary glands, adenovirus encoding human aquaporin-1 (AdhAQP1) directs human aquaporin-1 (hAQP1) expression in the apical and basolateral plasma membranes of salivary secretory cells, which may result in increased saliva production. hAQP1, a water channel protein, is one of several highly conserved water channel proteins that mediate water permeability in cells of water-transporting tissues.

Label: Adenovirus Encoding Human Aquaporin-1

NCI Thesaurus Code: C68932 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL374275  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Adenovirus Encoding Human Aquaporin-1
AdhAQP1

External Source Codes: 
PDQ Closed Trial Search ID 547184
PDQ Open Trial Search ID 547184 (check for NCI PDQ open clinical trial info)
NCI META CUI CL374275

Other Properties:
     Name Value (qualifiers indented underneath)
code C68932
Legacy_Concept_Name Adenovirus_Encoding_Human_Aquaporin-1
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C68932

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