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Version: 17.06d (Release date: 2017-06-26)
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Retinol (Code C68302)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Retinol

Definition: The fat soluble vitamin retinol. Vitamin A binds to and activates retinoid receptors (RARs), thereby inducing cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. Vitamin A plays an essential role in many physiologic processes, including proper functioning of the retina, growth and differentiation of target tissues, proper functioning of the reproductive organs, and modulation of immune function.

CRCH Definition: Retinoid with a hydroxyl group. Active form of vitamin A which can be converted to the other usable forms; retinal (an aldehyde) and retinoic acid (a carboxylic acid).

Label: Retinol

NCI Thesaurus Code: C68302 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0087161  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-nona-2,4,6,8-tetraen-1-ol
3,7-Dimethyl-9-(2,6, 6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
All Trans Retinol
Retinol
retinol
RETINOL

External Source Codes: 
CAS Registry Number 68-26-8 (see NLM ChemIDplus info)
CAS Registry Number 11103-57-4 (see NLM ChemIDplus info)
FDA UNII Code G2SH0XKK91
ChEBI ID CHEBI:17336 (see ChEBI info)
PDQ Closed Trial Search ID 39735
PDQ Open Trial Search ID 39735 (check for NCI PDQ open clinical trial info)
UMLS CUI C0087161

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C20H30O
code C68302
Contributing_Source CRCH
Contributing_Source FDA
INFOODS RETOL
Legacy_Concept_Name Retinol
Semantic_Type Vitamin
Unit mcg
USDA_ID 322

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C68302

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