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Version: 17.06d (Release date: 2017-06-26)
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Eicosapentaenoic Acid (Code C67080)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Eicosapentaenoic Acid

Definition: An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell populations. In addition, this agent may inhibit cyclooxygenase-2 (COX-2), resulting in inhibition of prostaglandin synthesis and prostaglandin-mediated inflammatory processes.

CRCH Definition: A class of polyunsaturated fatty acids with 20 carbons and 5 double bonds.

Display Name: Eicosapentaenoic Acid

Label: Eicosapentaenoic Acid

NCI Thesaurus Code: C67080 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0000545  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
All cis-5,8,11,14,17-Eicosapentaenoic Acid
Eicosapentaenoic Acid
EPA
Fatty Acid 20:5
Icosapentaenoic Acid
IPA
Timnodonic Acid

External Source Codes: 
CAS Registry Number 25378-27-2 (see NLM ChemIDplus info)
ChEBI ID CHEBI:36006 (see ChEBI info)
PDQ Closed Trial Search ID 537376
PDQ Open Trial Search ID 537376 (check for NCI PDQ open clinical trial info)
UMLS CUI C0000545

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C20H30O2
code C67080
Contributing_Source CRCH
Contributing_Source CTRP
Essential_Fatty_Acid Y
INFOODS F20D5
Legacy_Concept_Name Eicosapentaenoic_Acid
Macronutrient Y
Nutrient Y
Semantic_Type Organic Chemical
Unit g

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C67080

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