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Version: 17.06d (Release date: 2017-06-26)
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Technetium Tc-99m Medronate (Code C67060)

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Terms & Properties

Preferred Name: Technetium Tc-99m Medronate

Definition: A radiopharmaceutical containing methylene diphosphonate (medronate; MDP) complexed with the gamma-emitting radionuclide technetium Tc 99m with radioisotopic activity and hydroxyapatite affinity. Upon intravenous administration, skeletal uptake of technetium Tc 99m methylene diphosphonate occurs as a function of skeletal blood flow and osteogenic activity. The MDP moiety of this agent has affinity for hydroxyapatite crystals in bone with abnormal accumulation at sites with increased osteoid mineralization; labeling of MDP with Tc 99m allows scintigraphic imaging of areas of abnormal osteogenesis associated with malignant bone lesions.

Display Name: Technetium Tc-99m Medronate

Label: Technetium Tc-99m Medronate

NCI Thesaurus Code: C67060 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0039416  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(99m)Tc-Medronate
99mTc-MDP
TechneScan MDP
Technetium Tc-99m Medronate
TECHNETIUM TC-99M MEDRONATE
Technetium Tc 99m Methylene Diphosphonate

External Source Codes: 
CAS Registry Number 121524-79-6 (see NLM ChemIDplus info)
FDA UNII Code X89XV46R07
PDQ Closed Trial Search ID 537722
PDQ Open Trial Search ID 537722 (check for NCI PDQ open clinical trial info)
UMLS CUI C0039416

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula CH2O6P2.Tc
code C67060
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Technetium_Tc_99m_Medronate
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C67060

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