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Version: 16.10e (Release date: 2016-10-31)
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Kunecatechins Ointment (Code C67049)

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Terms & Properties

Preferred Name: Kunecatechins Ointment

Definition: A topical ointment containing a green tea polyphenol mixture (kunecatechins) with potential antiviral, antibacterial, antioxidant, and chemopreventive activities. Kunecatechins is a partially purified fraction of the aqueous extract of green tea leaves from Camellia sinensis and contains catechins and other green tea components. Catechins, polyphenolic antioxidant plant metabolites or flavonoids, comprise most of the drug substance in kunecatechins with epigallocatechin gallate (EGCG) present as the primary catechin. Catechins may inhibit basic functions of human papillomavirus (HPV), counteract specific changes in tumor cells, affect cell signaling, and stimulate the immune system. Topical application of kunecatechins ointment has been reported to reduce HPV-induced genital and anal warts through a not yet fully understood mechanism, which may involve anti-oxidative activity.

Label: Kunecatechins Ointment

NCI Thesaurus Code: C67049 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1816306  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Defined Green Tea Catechin Extract OIntment
Kunecatechins Ointment
Polyphenon E Ointment
Polyphenon E Topical Ointment
Veregen

External Source Codes: 
PDQ Closed Trial Search ID 533915
PDQ Open Trial Search ID 533915 (check for NCI PDQ open clinical trial info)
UMLS CUI C1816306

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Genital and Perianal Warts
code C67049
Legacy_Concept_Name Kunecatechin_Ointment
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C67049

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