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Version: 17.06d (Release date: 2017-06-26)
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Elisidepsin (Code C66949)

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Terms & Properties

Preferred Name: Elisidepsin

Definition: A synthetic cyclic depsipeptide of the kahalalides family with potential antineoplastic activity. PM02734 is a derivative of a natural marine compound extracted from the sacoglossan sea slug, Elysia rufescens. Although the exact mechanism of action has yet to be elucidated, elisidepsin exhibits anti-proliferative activity in a wide variety of cancer types, such as breast, colon, pancreas, lung, and prostate.

Display Name: Elisidepsin

Label: Elisidepsin

NCI Thesaurus Code: C66949 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C3467776  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Depsipeptide PM02734
L-Valine, N-((4S)-4-methyl-1-oxohexyl)-D-valyl-L-threonyl-L-valyl-D-valyl-D-prolyl-L-ornithyl-D-alloisoleucyl-D-allothreonyl-D-alloisoleucyl-D-valyl-L-phenylalanyl-(2Z)-2-amino-2-butenoyl-, (13-8)-lactone, 2,2,2-trifluoroacetate (1:1)

External Source Codes: 
CAS Registry Number 915713-02-9 (see NLM ChemIDplus info)
CAS Registry Number 681272-30-0 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 530791
PDQ Open Trial Search ID 530791 (check for NCI PDQ open clinical trial info)
UMLS CUI C3467776

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C57H87N7O15
code C66949
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Depsipeptide_PM02734
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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