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Version: 17.06d (Release date: 2017-06-26)
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Elisidepsin (Code C66949)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Elisidepsin

Definition: A synthetic cyclic depsipeptide of the kahalalides family with potential antineoplastic activity. PM02734 is a derivative of a natural marine compound extracted from the sacoglossan sea slug, Elysia rufescens. Although the exact mechanism of action has yet to be elucidated, elisidepsin exhibits anti-proliferative activity in a wide variety of cancer types, such as breast, colon, pancreas, lung, and prostate.

Display Name: Elisidepsin

Label: Elisidepsin

NCI Thesaurus Code: C66949 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C3467776  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Depsipeptide PM02734
Elisidepsin
ELISIDEPSIN
L-Valine, N-((4S)-4-methyl-1-oxohexyl)-D-valyl-L-threonyl-L-valyl-D-valyl-D-prolyl-L-ornithyl-D-alloisoleucyl-D-allothreonyl-D-alloisoleucyl-D-valyl-L-phenylalanyl-(2Z)-2-amino-2-butenoyl-, (13-8)-lactone, 2,2,2-trifluoroacetate (1:1)
PM02734

External Source Codes: 
CAS Registry Number 915713-02-9 (see NLM ChemIDplus info)
CAS Registry Number 681272-30-0 (see NLM ChemIDplus info)
FDA UNII Code 0FWR494EC9
PDQ Closed Trial Search ID 530791
PDQ Open Trial Search ID 530791 (check for NCI PDQ open clinical trial info)
UMLS CUI C3467776

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C57H87N7O15
code C66949
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Depsipeptide_PM02734
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C66949

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