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Version: 17.06d (Release date: 2017-06-26)
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Vinorelbine Tartrate Emulsion (Code C66943)

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Terms & Properties

Preferred Name: Vinorelbine Tartrate Emulsion

Definition: An emulsion containing the tartrate salt of the semisynthetic vinca alkaloid vinorelbine with antineoplastic activity. Vinorelbine binds to tubulin, inhibiting tubulin polymerization into microtubules; cell division is prevented, the cell cycle is arrested metaphase and cell death ensues. In this formulation vinorelbine is emulsified in a homogeneous suspension of nanoparticles, which protects the venous endothelium from coming into direct contact with the active ingredient, potentially reducing vinorelbine-associated venous toxicity at the venous injection site.

Display Name: Vinorelbine Tartrate Emulsion

Label: Vinorelbine Tartrate Emulsion

NCI Thesaurus Code: C66943 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1883539  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
ANX-530
Vinorelbine Tartrate Emulsion
Vinorelbine Tartrate Injectable Emulsion

External Source Codes: 
PDQ Closed Trial Search ID 538399
PDQ Open Trial Search ID 538399 (check for NCI PDQ open clinical trial info)
UMLS CUI C1883539

Other Properties:
     Name Value (qualifiers indented underneath)
code C66943
Contributing_Source CTRP
Legacy_Concept_Name Vinorelbine_Tartrate_Emulsion
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C66943

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