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Version: 17.06d (Release date: 2017-06-26)
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Morphine Sulfate (Code C669)

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Terms & Properties

Preferred Name: Morphine Sulfate

Definition: The sulfate salt of morphine, an opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions. In the central nervous and gastrointestinal systems, this agent has widespread effects including analgesia, anxiolysis, euphoria, sedation, respiratory depression, and gastrointestinal system smooth muscle contraction.

NCI-GLOSS Definition: A drug used to treat moderate to severe pain. It binds to opioid receptors in the central nervous system and some other tissues. Morphine sulfate is made from opium. It is a type of opiate and a type of analgesic agent.

Display Name: Morphine Sulfate

Label: Morphine Sulfate

NCI Thesaurus Code: C669 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0066814  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Avinza
Infumorph
Kadian
Morphine Sulfate
MORPHINE SULFATE
morphine sulfate
MSir
MS Contin
Oramorph
Oramorph SR
Roxanol
Statex SR

External Source Codes: 
CAS Registry Number 6211-15-0 (see NLM ChemIDplus info)
CAS Registry Number 64-31-3 (see NLM ChemIDplus info)
FDA UNII Code X3P646A2J0
ChEBI ID CHEBI:7003 (see ChEBI info)
ChEBI ID CHEBI:50731 (see ChEBI info)
NSC Code 11441 (see NCI DTP info)
PDQ Closed Trial Search ID 41804
PDQ Open Trial Search ID 41804 (check for NCI PDQ open clinical trial info)
UMLS CUI C0066814

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula 2C17H19NO3.5H2O.H2SO4
code C669
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Morphine
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C669

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