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Version: 17.06d (Release date: 2017-06-26)
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Mitolactol (Code C662)

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Terms & Properties

Preferred Name: Mitolactol

Definition: A synthetic derivative of hexitol with antineoplastic and radiosensitizing properties. Mitolactol alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA and RNA synthesis. (NCI04)

NCI-GLOSS Definition: An anticancer drug that belongs to the family of drugs called alkylating agents.

Label: Mitolactol

NCI Thesaurus Code: C662 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0026252  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
6-Dibromodideoxydulcitol
6-Dibromodulcitol
DBD
Dibromdicil
Dibromodulcitol
Elobromol
Mitolac
MITOLACTOL
Mitolactol
mitolactol

External Source Codes: 
CAS Registry Number 10318-26-0 (see NLM ChemIDplus info)
FDA UNII Code LJ2P1SIK8Y
NSC Code 104800 (see NCI DTP info)
PDQ Closed Trial Search ID 39216
PDQ Open Trial Search ID 39216 (check for NCI PDQ open clinical trial info)
UMLS CUI C0026252

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C6H12Br2O4
code C662
Contributing_Source FDA
Legacy_Concept_Name Mitolactol
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C662

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