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Version: 17.06d (Release date: 2017-06-26)
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Butylscopolamine Bromide (Code C65277)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Butylscopolamine Bromide

Definition: An orally available bromide salt form of butylscopolamine, a quaternary ammonium derivative of the alkaloid scopolamine, with anticholinergic property. Upon oral administration, hyoscine butylbromide binds to and blocks muscarinic receptors located on postganglionic parasympathetic nerve endings and on smooth muscle cells. This blocks the activity of acetylcholine (Ach) and causes its antispasmodic effect in the gastrointestinal (GI), urinary, uterine, and biliary tracts. This agent may also facilitate radiologic visualization of the GI tract.

Label: Butylscopolamine Bromide

NCI Thesaurus Code: C65277 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0006519  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Buscopan
Butylscopolamine Bromide
BUTYLSCOPOLAMINE BROMIDE
Oral Hyoscine Butylbromide

External Source Codes: 
CAS Registry Number 149-64-4 (see NLM ChemIDplus info)
FDA UNII Code 0GH9JX37C8
PDQ Closed Trial Search ID 690309
PDQ Open Trial Search ID 690309 (check for NCI PDQ open clinical trial info)
UMLS CUI C0006519

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C21H30NO4.Br
code C65277
Contributing_Source FDA
Legacy_Concept_Name Butylscopolamine_Bromide
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C65277

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