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Version: 17.06d (Release date: 2017-06-26)
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Therapeutic Melatonin (Code C632)

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Terms & Properties

Preferred Name: Therapeutic Melatonin

Definition: A therapeutic chemically synthesized form of the pineal indole melatonin with antioxidant properties. The pineal synthesis and secretion of melatonin, a serotonin-derived neurohormone, is dependent on beta-adrenergic receptor function. Melatonin is involved in numerous biological functions including circadian rhythm, sleep, the stress response, aging, and immunity.

Display Name: Therapeutic Melatonin

Label: Therapeutic Melatonin

NCI Thesaurus Code: C632 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1527137  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Circadin
MELATONIN
Melatonin
Melaxen
Therapeutic Melatonin

External Source Codes: 
CAS Registry Number 73-31-4 (see NLM ChemIDplus info)
FDA UNII Code JL5DK93RCL
ChEBI ID CHEBI:16796 (see ChEBI info)
NSC Code 113928 (see NCI DTP info)
NSC Code 56423 (see NCI DTP info)
PDQ Closed Trial Search ID 42346
PDQ Open Trial Search ID 42346 (check for NCI PDQ open clinical trial info)
UMLS CUI C1527137

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Sleep disorders in blind people with no light perception
Chemical_Formula C13H16N2O2
code C632
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Therapeutic_Melatonin
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C632

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