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Version: 17.06d (Release date: 2017-06-26)
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MAGE-A1, Her-2/neu, FBP Peptides Cancer Vaccine (Code C62775)

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Terms & Properties

Preferred Name: MAGE-A1, Her-2/neu, FBP Peptides Cancer Vaccine

Definition: A synthetic cancer vaccine comprised of multiple peptides derived from MAGE-1A, Her-2/neu, and folate binding protein (FBP), with potential immunostimulating and antineoplastic properties. MAGE-A1, Her-2/neu, and FBP proteins are simultaneously over-expressed in various cancer cell types, such as epithelial ovarian cancer. The MAGE-A1, Her-2/neu, FBP peptides cancer vaccine includes the peptides MAGE-A1:161-169, FBP:191-199, Her-2/neu:369-377, MAGE-A1:96-104, and Her-2/neu:754-762. Vaccination with this cancer vaccine may activate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing the corresponding antigens, resulting in tumor cell lysis.

Label: MAGE-A1, Her-2/neu, FBP Peptides Cancer Vaccine

NCI Thesaurus Code: C62775 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1831955  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
MAGE-A1, Her-2/neu, FBP Peptides Cancer Vaccine
MAGE-A1, Her-2/neu, FBP Peptides Ovarian Cancer Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 506045
PDQ Open Trial Search ID 506045 (check for NCI PDQ open clinical trial info)
UMLS CUI C1831955

Other Properties:
     Name Value (qualifiers indented underneath)
code C62775
Legacy_Concept_Name MAGE-A1_Her-2_neu_FBP_Peptide_Cancer_Vaccine
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C62775

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