skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.12d (Release date: 2017-12-26)
SearchBox Top
SearchBox Bottom
F-18 16 Alpha-Fluoroestradiol (Code C62541)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: F-18 16 Alpha-Fluoroestradiol

Definition: A radiopharmaceutical consisting of an estradiol analogue radiolabeled with the positron-emitting isotope fluorine F 18. F-18 16 alpha-fluoroestradiol is actively taken up in tumor cells expressing the estrogen receptor (ER), allowing visualization of ER-positive tumor cells with positron emission tomography (PET). Uptake of this agent depends upon the ER status of target tissues.

NCI-GLOSS Definition: A radiolabeled substance being studied as an imaging agent in breast cancer. F-18 16 alpha-fluoroestradiol binds to estrogen receptors and gives off radiation that can be detected by a PET scan. The PET scan forms an image that shows where cancer cells with estrogen receptors can be found in the body. It is a type of radioimaging agent.

Display Name: F-18 16 Alpha-Fluoroestradiol

Label: F-18 16 Alpha-Fluoroestradiol

NCI Thesaurus Code: C62541 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1831937  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
16 alpha-fluroestradiol-17 beta
F-18 16 Alpha-Fluoroestradiol
F-18 16 alpha-fluoroestradiol
F-18 FES
Fluorine-18 16 alpha-fluoroestradiol
Fluoroestradiol F-18

External Source Codes: 
CAS Registry Number 94153-53-4 (see NLM ChemIDplus info)
FDA UNII Code T32277KB09
PDQ Closed Trial Search ID 500062
PDQ Open Trial Search ID 500062 (check for NCI PDQ open clinical trial info)
UMLS CUI C1831937

Other Properties:
     Name Value (qualifiers indented underneath)
code C62541
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name F-18_16_Alpha-Fluoroestradiol
Semantic_Type Indicator, Reagent, or Diagnostic Aid
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


Mainbox Bottom