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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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siRNA-Expressing SV40 (Code C62536)

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Terms & Properties

Preferred Name: siRNA-Expressing SV40

Definition: A simian virus 40 (SV40)-based shuttle vector, encoding small interfering RNA (siRNA), with potential antineoplastic activity. The expression of siRNA in target tumor cells transfected with an siRNA-expressing SV40 vector may result in siRNA-mediated silencing of target oncogenes and, so, the inhibition of tumor cell growth and the induction of tumor cell death.

Label: siRNA-Expressing SV40

NCI Thesaurus Code: C62536 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL448851  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
siRNA-Expressing SV40

External Source Codes: 
PDQ Closed Trial Search ID 492229
PDQ Open Trial Search ID 492229 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C62536
Legacy_Concept_Name siRNA-Expressing_SV40_Vector
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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