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Version: 16.11d (Release date: 2016-11-28)
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18F-FHBG (Code C62533)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: 18F-FHBG

Definition: A fluorine-18-labeled acycloguanosine derivative substrate for herpes simplex virus type-1 thymidine kinase (HSV1-tk). 18F-FHBG is used as a reporter probe to image the expression of the herpes simplex virus type-1 thymidine kinase (HSV1-tk) gene in gene transfer therapy. HSV1-tk and HSV1-tk-metabolized 18F-FHBG co-localize, allowing positron emission tomography (PET) localization of HSV1-tk gene-transfected tissue and the assessment of gene transfer efficiency.

Display Name: 18F-FHBG

Label: 18F-FHBG

NCI Thesaurus Code: C62533 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1453307  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
18F-FHBG
9-(4-18F-Fluoro-3-[hydroxymethyl]butyl)guanine
Reporter Probe 18F-FHBG

External Source Codes: 
PDQ Closed Trial Search ID 488475
PDQ Open Trial Search ID 488475 (check for NCI PDQ open clinical trial info)
UMLS CUI C1453307

Other Properties:
Name Value (qualifiers indented underneath)
code C62533
Contributing_Source CTRP
Legacy_Concept_Name _18F-FHBG
Semantic_Type Chemical
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C62533

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