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Version: 17.06d (Release date: 2017-06-26)
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Indium In 111 Chimeric Monoclonal Antibody 806 (Code C62407)

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Terms & Properties

Preferred Name: Indium In 111 Chimeric Monoclonal Antibody 806

Definition: A recombinant chimeric, mouse-human monoclonal antibody IgG1, directed against the epidermal growth factor receptor (EGFR) and labeled with the radioisotope indium-111, with potential radioimaging activity. Indium 111 chimeric monoclonal antibody 806 binds to a specific epitope on EGFR-expressing tumor cells, allowing imaging of EGFR-expressing tumor cells using gamma scintigraphy. EGFR is a receptor tyrosine kinase that is involved in the regulation of cell growth and is found to be overexpressed on the cell surfaces of many tumor cell types.

Label: Indium In 111 Chimeric Monoclonal Antibody 806

NCI Thesaurus Code: C62407 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1831858  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
111-Indium-ch806
Indium 111 Chimeric Monoclonal Antibody 806
Indium In 111 Chimeric Monoclonal Antibody 806

External Source Codes: 
PDQ Closed Trial Search ID 487509
PDQ Open Trial Search ID 487509 (check for NCI PDQ open clinical trial info)
UMLS CUI C1831858

Other Properties:
     Name Value (qualifiers indented underneath)
code C62407
Legacy_Concept_Name Indium_In_111_Chimeric_Monoclonal_Antibody_806
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C62407

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