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Version: 17.06d (Release date: 2017-06-26)
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Tiotropium Bromide Monohydrate (Code C61974)

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Terms & Properties

Preferred Name: Tiotropium Bromide Monohydrate

Definition: The monohydrate bromide salt form of tiotropium, a quaternary ammonium derivative of atropine and a long-acting muscarinic receptor antagonist, with bronchodilating activity. Upon inhalation, tiotropium binds to and blocks mainly muscarinic M3 receptors located on smooth muscle cells, thereby preventing smooth muscle contraction.

Label: Tiotropium Bromide Monohydrate

NCI Thesaurus Code: C61974 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0905678  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1,4-Dihydro-3,5-Diiodo-1-Methyl-4-Oxopyridine-2,6-Dicarboxylic Acid
6Beta,7Beta-Epoxy-3Beta-Hydroxy-8-Methyl-1Alpha-H,5Alpha-H-Tropanium Bromide, Di-2-Thienylglycolate Monohydrate
Tiotropium Bromide Monohydrate

External Source Codes: 
CAS Registry Number 411207-31-3 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 682857
PDQ Open Trial Search ID 682857 (check for NCI PDQ open clinical trial info)
UMLS CUI C0905678

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C19H22NO4S2.Br.H2O
code C61974
Contributing_Source FDA
Legacy_Concept_Name Tiotropium_Bromide_Monohydrate
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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