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Version: 17.06d (Release date: 2017-06-26)
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Rifaximin (Code C61926)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Rifaximin

Definition: An orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting bacterial RNA synthesis and bacterial cell growth. As rifaximin is not well absorbed, its antibacterial activity is largely localized to the gastrointestinal tract.

Display Name: Rifaximin

Label: Rifaximin

NCI Thesaurus Code: C61926 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0073374  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Rifaximin
RIFAXIMIN
Xifaxan

External Source Codes: 
CAS Registry Number 80621-81-4 (see NLM ChemIDplus info)
FDA UNII Code L36O5T016N
PDQ Closed Trial Search ID 654589
PDQ Open Trial Search ID 654589 (check for NCI PDQ open clinical trial info)
UMLS CUI C0073374

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C43H51N3O11
code C61926
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Rifaximin
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61926

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