skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 16.10e (Release date: 2016-10-31)
SearchBox Top
SearchBox Bottom
Ethambutol (Code C61755)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Ethambutol

Definition: An antibiotic with bacteriostatic, antimicrobial and antitubercular properties. Ethambutol interferes with the biosynthesis of arabinogalactan, a major polysaccharide of the mycobacterial cell wall. It inhibits the polymerization of cell wall arabinan of arabinogalactan and lipoarabinomannan by blocking arabinosyl transferases and induces the accumulation of D-arabinofuranosyl-P-decaprenol, an intermediate in arabinan biosynthesis. This results in halting bacterial growth.

Label: Ethambutol

NCI Thesaurus Code: C61755 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0014964  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
ETHAMBUTOL
Ethambutol

External Source Codes: 
CAS Registry Number 74-55-5 (see NLM ChemIDplus info)
FDA UNII Code 8G167061QZ
ChEBI ID CHEBI:4877 (see ChEBI info)
UMLS CUI C0014964

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C10H24N2O2
code C61755
Contributing_Source FDA
Legacy_Concept_Name Ethambutol
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61755

Mainbox Bottom