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Version: 17.06d (Release date: 2017-06-26)
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Desvenlafaxine Succinate (Code C61704)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Desvenlafaxine Succinate

Definition: The succinate salt form of desvenlafaxine, a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state.

Label: Desvenlafaxine Succinate

NCI Thesaurus Code: C61704 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1742884  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Butanedioic Acid, Compound With 4-(2-(Dimethylamino)-1-(1-Hydroxycyclohexyl)Ethyl)Phenol (1:1), Monohydrate
Desvenlafaxine Succinate
DESVENLAFAXINE SUCCINATE
Pristiq

External Source Codes: 
CAS Registry Number 386750-22-7 (see NLM ChemIDplus info)
FDA UNII Code ZB22ENF0XR
UMLS CUI C1742884

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C16H25NO2.C4H6O4.H2O
code C61704
Contributing_Source FDA
Legacy_Concept_Name Desvenlafaxine_Succinate
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61704

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