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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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SU014813 (Code C61507)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: SU014813

Definition: An orally-active, tyrosine kinase receptor inhibitor with potential antitumor activity. SU014813 binds to and inhibits the phosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR) alpha and beta, c-Kit and Fms-related tyrosine kinase 3 (Flt-3). This leads to an inhibition of cellular proliferation and angiogenesis and an induction of apoptosis.

Label: SU014813

NCI Thesaurus Code: C61507 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1831849  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
SU014813

External Source Codes: 
PDQ Closed Trial Search ID 486831
PDQ Open Trial Search ID 486831 (check for NCI PDQ open clinical trial info)
UMLS CUI C1831849

Other Properties:
     Name Value (qualifiers indented underneath)
code C61507
Legacy_Concept_Name SU014813
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61507

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