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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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E7820 (Code C61501)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: E7820

Definition: A small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.

Display Name: E7820

Label: E7820

NCI Thesaurus Code: C61501 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1172515  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
E7820

External Source Codes: 
PDQ Closed Trial Search ID 363619
PDQ Open Trial Search ID 363619 (check for NCI PDQ open clinical trial info)
UMLS CUI C1172515

Other Properties:
     Name Value (qualifiers indented underneath)
code C61501
Contributing_Source CTRP
Legacy_Concept_Name E7820
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61501

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