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Version: 17.06d (Release date: 2017-06-26)
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Pegylated Anti-GFR Antibody Fragment (Code C61438)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Pegylated Anti-GFR Antibody Fragment

Definition: A pegylated, cross-linked, humanized divalent-Fab' antibody fragment directed against vascular endothelial growth factor receptor-2 (VEGFR-2) with potential antiangiogenic and antitumor activities. Pegylated anti-GFR antibody fragment binds to and inhibits VEGFR-2, which may inhibit angiogenesis and tumor cell proliferation. Multivalent Fab' antibody fragments may exhibit improved retention and internalization properties compared to their parent IgGs.

Label: Pegylated Anti-GFR Antibody Fragment

NCI Thesaurus Code: C61438 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1831765  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
CDP-791
Pegylated Anti-GFR Antibody Fragment

External Source Codes: 
PDQ Closed Trial Search ID 472077
PDQ Open Trial Search ID 472077 (check for NCI PDQ open clinical trial info)
UMLS CUI C1831765

Other Properties:
     Name Value (qualifiers indented underneath)
code C61438
Legacy_Concept_Name Pegylated_Anti-GRF_Antibody_Fragment
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61438

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