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Version: 16.11d (Release date: 2016-11-28)
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Delta-8-Tetrahydrocannabinol (Code C61312)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Delta-8-Tetrahydrocannabinol

Definition: An analogue of tetrahydrocannabinol (THC) with antiemetic, anxiolytic, appetite-stimulating, analgesic, and neuroprotective properties. Delta-8-tetrahydrocannabinol (delta-8-THC) binds to the cannabinoid G-protein coupled receptor CB1, located in the central nervous system; CB1 receptor activation inhibits adenyl cyclase, increases mitogen-activated protein kinase activities, modulates several potassium channel conductances and inhibits N- and P/Q-type Ca2+ channels. This agent exhibits a lower psychotropic potency than delta-9-tetrahydrocannabinol (delta-9-THC), the primary form of THC found in cannabis.

Label: Delta-8-Tetrahydrocannabinol

NCI Thesaurus Code: C61312 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0057341  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
.DELTA.8-TETRAHYDROCANNABINOL
Delta-8-Tetrahydrocannabinol
delta-8-THC

External Source Codes: 
CAS Registry Number 5957-75-5 (see NLM ChemIDplus info)
FDA UNII Code B49D0HH807
NSC Code 134453 (see NCI DTP info)
PDQ Closed Trial Search ID 485262
PDQ Open Trial Search ID 485262 (check for NCI PDQ open clinical trial info)
UMLS CUI C0057341

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C21H30O2
code C61312
Contributing_Source FDA
Legacy_Concept_Name Delta-8-Tetrahydrocannabinol
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61312

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