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Version: 17.12d (Release date: 2017-12-26)
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Demineralized Bone Matrix (Code C61085)

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Terms & Properties

Preferred Name: Demineralized Bone Matrix

Definition: Demineralized allograft bone with osteoinductive activity. Demineralized bone matrices are prepared by acid extraction of allograft bone, resulting in loss of most of the mineralized component but retention of collagen and noncollagenous proteins, including growth factors. The efficacy of a demineralized bone matrix (DBM) as a bone-graft substitute or extender may be related to the total amount of bone morphogenetic protein (BMP) present, and the ratios of the different BMPs present. BMPs belong to the transforming growth factor (TGF) superfamily of proteins.

Label: Demineralized Bone Matrix

NCI Thesaurus Code: C61085 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1832069  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Demineralized Bone Matrix

External Source Codes: 
PDQ Closed Trial Search ID 476316
PDQ Open Trial Search ID 476316 (check for NCI PDQ open clinical trial info)
UMLS CUI C1832069

Other Properties:
     Name Value (qualifiers indented underneath)
code C61085
Legacy_Concept_Name Demineralized_Bone_Matrix
Semantic_Type Biomedical or Dental Material

Additional Concept Data: 
Defined Fully by Roles: No  


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