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Version: 17.06d (Release date: 2017-06-26)
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Levamisole Hydrochloride (Code C610)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Levamisole Hydrochloride

Definition: The hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunomodulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis.

Display Name: Levamisole Hydrochloride

Label: Levamisole Hydrochloride

NCI Thesaurus Code: C610 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0733383  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole Monohydrochloride
Ascaridil
Cloridrato de Levamizol
Decaris
Ergamisol
Ergamisole
ICI-59623
Immunol
Ketrax
l-Tetramisole hydrochloride
l-Tetramisole Hydrochloride
Levamisole Hydrochloride
LEVAMISOLE HYDROCHLORIDE
R-12564
RP-20605
R 12564
Solaskil
Tramisol
Trimisol

External Source Codes: 
CAS Registry Number 16595-80-5 (see NLM ChemIDplus info)
FDA UNII Code DL9055K809
NSC Code 177023 (see NCI DTP info)
PDQ Closed Trial Search ID 39058
PDQ Open Trial Search ID 39058 (check for NCI PDQ open clinical trial info)
UMLS CUI C0733383

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Stage III Colon Cancer
Chemical_Formula C11H12N2S.HCl
code C610
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Levamisole
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C610

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