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Version: 17.06d (Release date: 2017-06-26)
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F-18 Fluoroethyltyrosine (Code C60818)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: F-18 Fluoroethyltyrosine

Definition: An amino acid analog radiolabeled with fluorine F 18, a positron emitting isotope, used as a tracer in positron emission tomography (PET). Reflecting the increased amino acid transport capacity of tumor cells, F-18 fluroethyltyrosine (F-18 FET) is actively taken up in tumor cells via the amino acid transport system, but is neither incorporated into proteins nor readily degraded, resulting in high intracellular concentrations of this imaging agent. Radiolabeled amino acid-based agents are useful in PET brain tumor imaging because F-18 fluoro-deoxyglucose (F-18 FDG), commonly used in PET tumor imaging, is relatively insensitive for detecting tumors in the brain due to high levels of glycolytic metabolism in the normal cortex and to a lesser extent in white matter.

Label: F-18 Fluoroethyltyrosine

NCI Thesaurus Code: C60818 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1831729  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
18F-FET
18FET
2'-[F18] Fluoro-ethyl-L-tyrosine
[18F]-Fluoro-ethyl-L-tyrosine
F-18 Fluoroethyltyrosine
Fluorine-18 2'-Fluoroethyl-L-tyrosine
Fluorine-18 Fluoroethyl-L-Tyrosine
Fluoroethyl-L-tyrosine F 18
Fluoroethyltyrosine F18
O-(2[F18]fluoroethyl)-L-tyrosine
O-2'-[F18]-Fluoroethyl-L-tyrosine

External Source Codes: 
PDQ Closed Trial Search ID 467177
PDQ Open Trial Search ID 467177 (check for NCI PDQ open clinical trial info)
UMLS CUI C1831729

Other Properties:
     Name Value (qualifiers indented underneath)
code C60818
Legacy_Concept_Name Fluoroethyl-L-tyrosine_F_18
Semantic_Type Indicator, Reagent, or Diagnostic Aid
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C60818

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