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Version: 17.06d (Release date: 2017-06-26)
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Therapeutic Hydrocortisone (Code C555)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Therapeutic Hydrocortisone

Definition: A synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects. As a glucocorticoid receptor agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. (NCI04)

NCI-GLOSS Definition: A drug used to relieve the symptoms of certain hormone shortages and to suppress an immune response.

Display Name: Therapeutic Hydrocortisone

Label: Therapeutic Hydrocortisone

NCI Thesaurus Code: C555 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0020268  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
Aeroseb-HC
Barseb-HC
Barseb HC
Cetacort
Cort-Dome
Cortef
Cortenema
Cortifan
Cortisol
Cortispray
Cortril
Dermacort
Domolene
Eldecort
Hautosone
Heb-Cort
Hydrocortisone
HYDROCORTISONE
hydrocortisone
Hydrocortone
Hytone
Komed-HC
Nutracort
Proctocort
Rectoid
Therapeutic Hydrocortisone

External Source Codes: 
CAS Registry Number 50-23-7 (see NLM ChemIDplus info)
FDA UNII Code WI4X0X7BPJ
ChEBI ID CHEBI:17650 (see ChEBI info)
NSC Code 10483 (see NCI DTP info)
NSC Code 10482 (see NCI DTP info)
PDQ Closed Trial Search ID 39274
PDQ Open Trial Search ID 39274 (check for NCI PDQ open clinical trial info)
UMLS CUI C0020268

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C21H30O5
code C555
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Therapeutic_Hydrocortisone
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C555

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