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Version: 16.10e (Release date: 2016-10-31)
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G250 Peptide Vaccine (Code C53410)

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Terms & Properties

Preferred Name: G250 Peptide Vaccine

Definition: A cancer vaccine containing of a synthetic form of the renal cell carcinoma (RCC)-associated antigen G250 with potential antineoplastic activity. Vaccination with G250 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the G250 antigen, resulting in decreased tumor growth. Found in the majority of renal cell carcinomas, G250 is a cell surface tumor-associated antigen (TAA) that contains an HLA-A2.1-restricted epitope that is recognized by CTLs.

Label: G250 Peptide Vaccine

NCI Thesaurus Code: C53410 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1711251  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
G250 Peptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 465193
PDQ Open Trial Search ID 465193 (check for NCI PDQ open clinical trial info)
UMLS CUI C1711251

Other Properties:
Name Value (qualifiers indented underneath)
code C53410
Legacy_Concept_Name G250_Peptide_Vaccine
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C53410

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