skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.12d (Release date: 2017-12-26)
SearchBox Top
SearchBox Bottom
Bemiparin Sodium (Code C53400)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Bemiparin Sodium

Definition: The sodium salt of bemiparin, a second generation, synthetic, low-molecular-weight heparin (LMWH) with anticoagulant activity. Derived, after depolymerisation and fractionation, from medical-grade porcine unfractionated heparin (UFH), bemiparin has an average molecular weight of 3,600 daltons and has a higher anti-factor Xa/anti-factor IIa ratio (8:1) than first-generation LMWHs. This anticoagulant binds to antithrombin III, thereby enhancing the inactivation of activated factor X (Factor Xa) and, to a lesser extent, activated factor II (Factor IIa). Compared to unfractionated heparins, the use of bemiparin is associated with lower incidences of major bleeding, osteoporosis, and heparin-induced thrombocytopenia. Bemiparin also promotes a greater release of tissue factor pathway inhibitor than UFH or dalteparin.

Label: Bemiparin Sodium

NCI Thesaurus Code: C53400 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1529923  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Bemiparin Sodium

External Source Codes: 
PDQ Closed Trial Search ID 463367
PDQ Open Trial Search ID 463367 (check for NCI PDQ open clinical trial info)
UMLS CUI C1529923

Other Properties:
     Name Value (qualifiers indented underneath)
code C53400
Contributing_Source FDA
Legacy_Concept_Name Bemiparin_Sodium
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


Mainbox Bottom