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National Cancer Institute
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Version: 17.12d (Release date: 2017-12-26)
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IRX-2 (Code C53396)

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Terms & Properties

Preferred Name: IRX-2

Definition: A cell-free mixture comprised of a variety of naturally-derived cytokines obtained from normal, unrelated donor lymphocytes with potential immunostimulatory activity. The cytokines in IRX-2, including interleukin (IL)-1, -2, -6, -8, -10, -12, tumor necrosis factor alpha (TNF-a), interferon-gamma (IFN-g) and colony stimulating factors (CSFs), play vital roles in regulating cellular immunity and may synergistically stimulate a cellular immune response against tumor cells.

Label: IRX-2

NCI Thesaurus Code: C53396 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0758290  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
PDQ Closed Trial Search ID 462160
PDQ Open Trial Search ID 462160 (check for NCI PDQ open clinical trial info)
UMLS CUI C0758290

Other Properties:
     Name Value (qualifiers indented underneath)
code C53396
Legacy_Concept_Name IRX-2
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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