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Version: 17.06d (Release date: 2017-06-26)
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Glycine (Code C524)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Glycine

Definition: A non-essential, non-polar, non-optical, glucogenic amino acid. Glycine, an inhibitory neurotransmitter in the CNS, triggers chloride ion influx via ionotropic receptors, thereby creating an inhibitory post-synaptic potential. In contrast, this agent also acts as a co-agonist, along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is an important component and precursor for many macromolecules in the cells.

CRCH Definition: Amino acid with side chain -H.

Label: Glycine

NCI Thesaurus Code: C524 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0017890  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Aminoethanoic acid
Gly
Glycine
GLYCINE

External Source Codes: 
CAS Registry Number 56-40-6 (see NLM ChemIDplus info)
FDA UNII Code TE7660XO1C
ChEBI ID CHEBI:15428 (see ChEBI info)
NSC Code 25936 (see NCI DTP info)
PDQ Closed Trial Search ID 41347
PDQ Open Trial Search ID 41347 (check for NCI PDQ open clinical trial info)
UMLS CUI C0017890

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C2H5NO2
code C524
Contributing_Source CRCH
Contributing_Source FDA
Legacy_Concept_Name Glycine
Semantic_Type Amino Acid, Peptide, or Protein

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C524

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