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Version: 17.06d (Release date: 2017-06-26)
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Menatetrenone (Code C52194)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Menatetrenone

Definition: A menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act by modulating the signalling of certain tyrosine kinases, thereby affecting several transcription factors including c-myc and c-fos. This agent inhibits tumor cell growth by inducing apoptosis and cell cycle arrest.

Label: Menatetrenone

NCI Thesaurus Code: C52194 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0065936  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
2-Methyl-3-trans-tetraprenyl-1,4-naphthoquinone
E0167
Menaquinone-4
Menaquinone K4
MENATETRENONE
Menatetrenone
Vitamin MK 4

External Source Codes: 
CAS Registry Number 863-61-6 (see NLM ChemIDplus info)
FDA UNII Code 27Y876D139
PDQ Closed Trial Search ID 459755
PDQ Open Trial Search ID 459755 (check for NCI PDQ open clinical trial info)
UMLS CUI C0065936

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C31H40O2
code C52194
Contributing_Source FDA
Legacy_Concept_Name Menatetrenone
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C52194

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