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Version: 17.06d (Release date: 2017-06-26)
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Ex Vivo-Expanded HER2-Specific T Cells (Code C52192)

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Terms & Properties

Preferred Name: Ex Vivo-Expanded HER2-Specific T Cells

Definition: T cells specific for the human epidermal growth factor receptor 2 (HER2) with potential immunopotentiating activity. T cells directed against HER2, overexpressed on many tumor cells, are collected from HER2-expressing tumor tissue, expanded ex vivo and, then re-introduced in the patient. Re-introduction of ex vivo-expanded HER2-specific T cells may enhance the cytotoxic T cell response against tumor cells overexpressing HER2, resulting in inhibition of tumor growth.

Display Name: Ex Vivo-Expanded HER2-Specific T Cells

Label: Ex Vivo-Expanded HER2-Specific T Cells

NCI Thesaurus Code: C52192 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1708270  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Ex Vivo-Expanded HER2-Specific T Cells
HER2 Specific T-Cells

External Source Codes: 
PDQ Closed Trial Search ID 459973
PDQ Open Trial Search ID 459973 (check for NCI PDQ open clinical trial info)
UMLS CUI C1708270

Other Properties:
     Name Value (qualifiers indented underneath)
code C52192
Contributing_Source CTRP
Legacy_Concept_Name HER2_Specific_T-Cell
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C52192

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