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Version: 17.06d (Release date: 2017-06-26)
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Etoricoxib (Code C52188)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Etoricoxib

Definition: A synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.

Label: Etoricoxib

NCI Thesaurus Code: C52188 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0972314  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
5-Chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl) Pyridine
Arcoxia
Etoricoxib
ETORICOXIB
L-791456
MK-0663

External Source Codes: 
CAS Registry Number 202409-33-4 (see NLM ChemIDplus info)
FDA UNII Code WRX4NFY03R
ChEBI ID CHEBI:6339 (see ChEBI info)
PDQ Closed Trial Search ID 462092
PDQ Open Trial Search ID 462092 (check for NCI PDQ open clinical trial info)
UMLS CUI C0972314

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C18H15ClN2O2S
code C52188
Contributing_Source FDA
Legacy_Concept_Name Etoricoxib
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C52188

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