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Version: 17.06d (Release date: 2017-06-26)
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Basiliximab (Code C52186)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Basiliximab

Definition: A recombinant, chimeric, human-murine monoclonal antibody directed against the alpha subunit of the interleukin-2 receptor (IL-2R alpha) with immunosuppressant activity. Basiliximab selectively binds to and blocks IL-2R alpha, expressed on the surface of activated T-lymphocytes, thereby preventing interleukin-2 binding and inhibiting the interleukin-2-mediated activation of lymphocytes.

Display Name: Basiliximab

Label: Basiliximab

NCI Thesaurus Code: C52186 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0676831  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Basiliximab
BASILIXIMAB
SDZ-CHI-621
Simulect

External Source Codes: 
CAS Registry Number 179045-86-4 (see NLM ChemIDplus info)
FDA UNII Code 9927MT646M
ChEBI ID CHEBI:63583 (see ChEBI info)
PDQ Closed Trial Search ID 459956
PDQ Open Trial Search ID 459956 (check for NCI PDQ open clinical trial info)
UMLS CUI C0676831

Other Properties:
     Name Value (qualifiers indented underneath)
code C52186
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Basiliximab
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C52186

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