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National Cancer Institute
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Version: 17.12d (Release date: 2017-12-26)
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AG-024322 (Code C52182)

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Terms & Properties

Preferred Name: AG-024322

Definition: A cyclin-dependent kinase (CDK) inhibitor with antineoplastic activity. AG-024322 selectively inhibits cyclin-dependent kinases (particularly CDK1,2 and 4), enzymes that regulate cell cycle progression. Inhibition of CDK may result in cell cycle arrest, induction of apoptosis, and inhibition of DNA replication and tumor cell proliferation.

Label: AG-024322

NCI Thesaurus Code: C52182 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1706655  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
PDQ Closed Trial Search ID 459491
PDQ Open Trial Search ID 459491 (check for NCI PDQ open clinical trial info)
UMLS CUI C1706655

Other Properties:
     Name Value (qualifiers indented underneath)
code C52182
Legacy_Concept_Name AG-024322
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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