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Version: 17.06d (Release date: 2017-06-26)
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Fluoxymesterone (Code C507)

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Terms & Properties

Preferred Name: Fluoxymesterone

Definition: A halogenated derivative of 17-alpha-methyltestosterone. Similar to testosterone, fluoxymesterone binds to and activates specific nuclear receptors, resulting in an increase in protein anabolism, a decrease in amino acid catabolism, and retention of nitrogen, potassium, and phosphorus. This agent also may competitively inhibit prolactin receptors and estrogen receptors, thereby inhibiting the growth of hormone-dependent tumor lines. Fluoxymesterone is approximately five times more potent than methyltestosterone. (NCI04)

Label: Fluoxymesterone

NCI Thesaurus Code: C507 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0016366  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(11Beta,17beta)-9-fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one
11Beta,17beta-dihydroxy-9alpha-fluoro-17alpha-methyl-4-androsten-3-one
9Alpha-fluoro-11beta-hydroxy-17alpha-methyltestosterone
Androfluorene
Android-F
Androsterolo
FLUOXYMESTERONE
Fluoxymesterone
FXM
Halodrin
Halotestin
Ora-Testryl
Ora-testryl
Oratestin
Ora Testryl
Stenox
Testoral
Ultandren

External Source Codes: 
CAS Registry Number 76-43-7 (see NLM ChemIDplus info)
FDA UNII Code 9JU12S4YFY
ChEBI ID CHEBI:5120 (see ChEBI info)
NSC Code 12165 (see NCI DTP info)
PDQ Closed Trial Search ID 494707
PDQ Open Trial Search ID 494707 (check for NCI PDQ open clinical trial info)
UMLS CUI C0016366

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C20H29FO3
code C507
Contributing_Source FDA
Legacy_Concept_Name Fluoxymesterone
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C507

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