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Version: 17.06d (Release date: 2017-06-26)
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Recombinant DNA-L523S Vaccine (Code C49290)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Recombinant DNA-L523S Vaccine

Definition: A plasmid DNA encoding human L523S, an RNA-binding protein that belongs to the KOC (K homology domain containing protein overexpressed in cancer) family, with potential antineoplastic activity. Vaccination with L523S DNA may stimulate a cytotoxic T lymphocytes (CTL) response against tumor cells that express the L523S protein. As an oncofetal protein, L523S is normally expressed in early embryonic tissue, but is overexpressed in certain cancer cell types.

Label: Recombinant DNA-L523S Vaccine

NCI Thesaurus Code: C49290 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1709856  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
pVAX/L523S
Recombinant DNA-L523S Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 353188
PDQ Open Trial Search ID 353188 (check for NCI PDQ open clinical trial info)
UMLS CUI C1709856

Other Properties:
     Name Value (qualifiers indented underneath)
code C49290
Legacy_Concept_Name Recombinant_DNA-L523S_Vaccine
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C49290

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