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Version: 17.06d (Release date: 2017-06-26)
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Lenograstim (Code C49234)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Lenograstim

Definition: A glycosylated form of a recombinant therapeutic agent which is chemically identical to or similar to an endogenous human granulocyte colony-stimulating factor (G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions.

Label: Lenograstim

NCI Thesaurus Code: C49234 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0218640  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Glycosylated Recombinant G-CSF
Glycosylated Recombinant Granulocyte Colony-Stimulating Factor
Granocyte
Lenograstim
LENOGRASTIM
Neutrogin

External Source Codes: 
CAS Registry Number 135968-09-1 (see NLM ChemIDplus info)
FDA UNII Code 6WS4C399GB
PDQ Closed Trial Search ID 536232
PDQ Open Trial Search ID 536232 (check for NCI PDQ open clinical trial info)
UMLS CUI C0218640

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Chemotherapy-induced neutropenia
code C49234
Contributing_Source FDA
Legacy_Concept_Name Lenograstim
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C49234

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