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Version: 17.12d (Release date: 2017-12-26)
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Lenograstim (Code C49234)

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Terms & Properties

Preferred Name: Lenograstim

Definition: A glycosylated form of a recombinant therapeutic agent which is chemically identical to or similar to an endogenous human granulocyte colony-stimulating factor (G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions.

Label: Lenograstim

NCI Thesaurus Code: C49234 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0218640  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Glycosylated Recombinant G-CSF
Glycosylated Recombinant Granulocyte Colony-Stimulating Factor

External Source Codes: 
CAS Registry Number 135968-09-1 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 536232
PDQ Open Trial Search ID 536232 (check for NCI PDQ open clinical trial info)
UMLS CUI C0218640

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Chemotherapy-induced neutropenia
code C49234
Contributing_Source FDA
Legacy_Concept_Name Lenograstim
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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