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Version: 17.06d (Release date: 2017-06-26)
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Recombinant dHER2 Vaccine (Code C49177)

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Terms & Properties

Preferred Name: Recombinant dHER2 Vaccine

Definition: A cancer vaccine consisting of a truncated recombinant HER2 peptide (dHER2) with potential antineoplastic activity. Upon administration, recombinant dHER2 vaccine may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against tumor cells that overexpress the HER2 protein, resulting in tumor cell lysis. The HER2 protein is a tumor-associated antigen (TAA) that is overexpressed in a variety of cancers. dHER2 includes the extracellular domain (ECD) and a part of the intracellular domain (ICD) of the HER2 protein.

Label: Recombinant dHER2 Vaccine

NCI Thesaurus Code: C49177 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL448761  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Recombinant dHER2 Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 454589
PDQ Open Trial Search ID 454589 (check for NCI PDQ open clinical trial info)
NCI META CUI CL448761

Other Properties:
     Name Value (qualifiers indented underneath)
code C49177
Legacy_Concept_Name Recombinant_dHER2_Vaccine
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C49177

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