|Notch Signaling Pathway Inhibitor MK0752 (Code C49175)|
|Terms & Properties|
Preferred Name: Notch Signaling Pathway Inhibitor MK0752
Definition: A synthetic small molecule with potential antineoplastic activity. MK0752 inhibits the Notch signaling pathway, which may result in induction of growth arrest and apoptosis in tumor cells in which the Notch signaling pathway is overactivated. The Notch signaling pathway plays an important role in cell-fate determination, cell survival, and cell proliferation.
NCI-GLOSS Definition: A substance being studied in the treatment of cancer. It blocks signals between growing cells and may kill cancer cells. It is a type of signal transduction inhibitor.
Display Name: Notch Signaling Pathway Inhibitor MK0752
Label: Notch Signaling Pathway Inhibitor MK0752
NCI Metathesaurus Link: C1708824 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
|Notch Signaling Pathway Inhibitor MK0752|
External Source Codes:
|PDQ Closed Trial Search ID||446541|
|PDQ Open Trial Search ID||446541 (check for NCI PDQ open clinical trial info)|
|Name||Value (qualifiers indented underneath)|
Additional Concept Data:
|Defined Fully by Roles: No|