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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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MK0731 (Code C49174)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: MK0731

Definition: A synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP.

Label: MK0731

NCI Thesaurus Code: C49174 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1708823  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
MK0731

External Source Codes: 
PDQ Closed Trial Search ID 446551
PDQ Open Trial Search ID 446551 (check for NCI PDQ open clinical trial info)
UMLS CUI C1708823

Other Properties:
     Name Value (qualifiers indented underneath)
code C49174
Legacy_Concept_Name MK0731
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C49174

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